Human Bone Marrow Stromal Cells Lose Immunosuppressive and Anti-inflammatory Properties upon Oncogenic Transformation

@inproceedings{Rodrguez2014HumanBM,
  title={Human Bone Marrow Stromal Cells Lose Immunosuppressive and Anti-inflammatory Properties upon Oncogenic Transformation},
  author={Ren{\'e} Miguel P{\'e}rez Rodr{\'i}guez and Michael Rosu-Myles and Marcos Jes{\'u}s Ara{\'u}zo-Bravo and Ang{\'e}lica Horrillo and Qiuwei Pan and Elena Gonz{\'a}lez-Rey and Mario Delgado and P. J. Men{\'e}ndez},
  booktitle={Stem cell reports},
  year={2014}
}
Because of their immunomodulatory properties, human bone marrow stromal cells (hBMSCs) represent promising stem cells for treatment of immune disorders. hBMSCs expansion precedes their clinical use, so the possibility that hBMSCs undergo spontaneous transformation upon long-term culture should be addressed. Whether hBMSCs retain immunosuppressive and anti… CONTINUE READING

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