Human Bone Marrow Mesenchymal Stem Cells Display Anti-Cancer Activity in SCID Mice Bearing Disseminated Non-Hodgkin's Lymphoma Xenografts

@inproceedings{Secchiero2010HumanBM,
  title={Human Bone Marrow Mesenchymal Stem Cells Display Anti-Cancer Activity in SCID Mice Bearing Disseminated Non-Hodgkin's Lymphoma Xenografts},
  author={Paola Secchiero and Sonia Zorzet and Claudio Tripodo and Federica Corallini and Elisabetta Melloni and Lorenzo Caruso and Raffaella Bosco and Sabrina Ingrao and Barbara Zavan and Giorgio Zauli},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND Although multimodality treatment can induce high rate of remission in many subtypes of non-Hodgkin's lymphoma (NHL), significant proportions of patients relapse with incurable disease. The effect of human bone marrow (BM) mesenchymal stem cells (MSC) on tumor cell growth is controversial, and no specific information is available on the effect of BM-MSC on NHL. METHODOLOGY/PRINCIPAL FINDINGS The effect of BM-MSC was analyzed in two in vivo models of disseminated non-Hodgkin's… CONTINUE READING

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