Human Body Epigenome Maps Reveal Noncanonical DNA Methylation Variation

@inproceedings{Schultz2015HumanBE,
  title={Human Body Epigenome Maps Reveal Noncanonical DNA Methylation Variation},
  author={Matthew D. Schultz and Yupeng He and John W. Whitaker and Manoj Hariharan and Eran A. Mukamel and Danny Leung and Nisha Rajagopal and Joseph R Nery and Mark A. Urich and Huaming Chen and Shin Lin and Yiing Lin and Inkyung Jung and Anthony D. Schmitt and Siddarth Selvaraj and Bing Ren and Terrence J. Sejnowski and Wei Wang and Joseph R. Ecker},
  booktitle={Nature},
  year={2015}
}
Understanding the diversity of human tissues is fundamental to disease and requires linking genetic information, which is identical in most of an individual’s cells, with epigenetic mechanisms that could have tissue-specific roles. Surveys of DNA methylation in human tissues have established a complex landscape including both tissue-specific and invariant methylation patterns. Here we report high coverage methylomes that catalogue cytosine methylation in all contexts for the major human organ… CONTINUE READING

Figures and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 188 CITATIONS, ESTIMATED 88% COVERAGE

Epigenomic landscapes of retinal rods and cones

  • eLife
  • 2016
VIEW 9 EXCERPTS
CITES RESULTS, BACKGROUND & METHODS

DNA Methylation Landscape Reflects the Spatial Organization of Chromatin in Different Cells.

  • Biophysical journal
  • 2017
VIEW 4 EXCERPTS
CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

Epigenomic Diversity in a Global Collection of Arabidopsis thaliana Accessions

Taiji Kawakatsu, Shao-shan Carol Huang, +20 authors Joseph R. Ecker
  • Cell
  • 2016
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS

Inheritance of DNA methylation level in healthy human tissues

VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2015
2019

CITATION STATISTICS

  • 13 Highly Influenced Citations

  • Averaged 41 Citations per year from 2017 through 2019

References

Publications referenced by this paper.