Human Antibody Production in Transgenic Animals


Fully human antibodies from transgenic animals account for an increasing number of new therapeutics. After immunization, diverse human monoclonal antibodies of high affinity can be obtained from transgenic rodents, while large animals, such as transchromosomic cattle, have produced respectable amounts of specific human immunoglobulin (Ig) in serum. Several… (More)
DOI: 10.1007/s00005-014-0322-x


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@inproceedings{Brggemann2014HumanAP, title={Human Antibody Production in Transgenic Animals}, author={Marianne Br{\"{u}ggemann and Michael J. Osborn and Biao Ma and Jasvinder Hayre and Suzanne Avis and Brian Lundstrom and Roland Buelow}, booktitle={Archivum Immunologiae et Therapiae Experimentalis}, year={2014} }