Human African trypanosomiasis in endemic populations and travellers
@article{Blum2011HumanAT, title={Human African trypanosomiasis in endemic populations and travellers}, author={Johannes A. Blum and Andreas Neumayr and C. F. Hatz}, journal={European Journal of Clinical Microbiology \& Infectious Diseases}, year={2011}, volume={31}, pages={905-913} }
Human African trypanosomiasis (HAT) or sleeping sickness is caused by the protozoan parasites Trypanosoma brucei (T.b.) gambiense (West African form) and T.b. rhodesiense (East African form) that are transmitted by the bite of the tsetse fly, Glossina spp.. Whereas most patients in endemic populations are infected with T.b. gambiense, most tourists are infected with T.b. rhodesiense. In endemic populations, T.b. gambiense HAT is characterized by chronic and intermittent fever, headache…
54 Citations
Human African Trypanosomiasis: A Highly Neglected Neurological Disease
- Medicine
- 2014
The recent decline in the number of reported new HAT cases should not foster further neglect of this highly neglected nervous system infection, and stage biomarkers and safer therapy are urgently needed.
Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness)
- MedicineThe Lancet Neurology
- 2013
Human African trypanosomiasis in travellers to Kenya.
- MedicineEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
- 2012
In this issue, two cases are described of human African trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense. They occurred recently in European tourists returning from Masai Mara area, Kenya,…
Biology of human pathogenic trypanosomatids: epidemiology, lifecycle and ultrastructure.
- Biology, MedicineSub-cellular biochemistry
- 2014
These pathogenic trypanosomatids alternate between invertebrate and vertebrate hosts throughout their lifecycles, and different developmental stages can live inside the host cells and circulate in the bloodstream or in the insect gut.
Human African trypanosomiasis in non-endemic countries.
- MedicineClinical medicine
- 2015
The clinical presentation, diagnosis and treatment of the two forms of HAT are outlined, Rhodesiense HAT is an acute illness that presents in tourists who have recently visited game parks in Eastern or Southern Africa, whereas GambienseHAT has a more chronic clinical course.
Human African trypanosomiasis with 7-year incubation period: clinical, laboratory and neuroimaging findings.
- MedicineParasitology international
- 2014
Leishmania and Trypanosoma
- Medicine, Biology
- 2011
Clinicians may have to use many different diagnostic methods to detect the infection due to the low number of parasites in specimens, and some infections may self-cure, while others will need to be treated depending on the number of lesions and whether the leishmaniasis is mucocutaneous or visceral.
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