534 Citations
Human african trypanosomiasis: current standing and challenges
- Medicine
- 2020
Information is compiled on the history of the clinical aspects of HAT, its epidemiology, diagnosis, therapy, and prophylaxis, as well as updating information on the current panorama and perspectives regarding the disease.
Human African Trypanosomiasis in a Spanish traveler returning from Tanzania
- MedicinePLoS neglected tropical diseases
- 2017
Clinicians should be aware of the potential presentation of patients with HAT and recommend an accurate anamnesis, including travel history and incubation and prodromal periods, together with a thorough physical examination, to guide the diagnostic workup.
Human African trypanosomiasis: the current situation in endemic regions and the risks for non-endemic regions from imported cases
- MedicineParasitology
- 2020
The data on HAT incidence is explored and interpret and find no positive correlation between the number of HAT cases from endemic and non-endemic countries and this data will provide useful information for better understanding the imported cases of H AT globally in the post-elimination phase.
Update on human African trypanosomiasis (sleeping sickness)
- Medicine, BiologyJournal of Neurology
- 2019
An overview of some important recent developments in human African trypanosomiasis covers various aspects including a reduction in disease incidence, newly recognised parasite reservoir sites in humans, disease outcome, novel diagnostic methods, new and improved treatment, and disease neuropathogenesis.
Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis
- Medicine, BiologyFront. Immunol.
- 2019
Clinical features of HAT are diverse and non-specific with early-stage symptoms common to several infections endemic within sub-Saharan Africa which may result in a delayed or mistaken diagnosis and further research is required to develop better diagnostic and staging techniques and safer more efficacious drug regimens.
Human African Trypanosomiasis in the Kafue National Park, Zambia
- Environmental SciencePLoS neglected tropical diseases
- 2016
A case of HAT is described in an adult male from the Kafue National Park, which is a vast and continuous wildlife conservation area located in the central part of Zambia and rich in biodiversity of high biomass.
Human African trypanosomiasis: current status and eradication efforts.
- Medicine
- 2020
Despite the progress, the danger of disease resurgence is well-known for HAT and continued surveillance and treatment availability is essential, and many uncertainties regarding HAT transmission remain and combine to make potential disease eradication a complete unknown.
Role of Serodiagnosis of Human African Trypanosomiasis (Sleeping Sickness)
- Medicine
- 2017
Human African trypanosomiasis (HAT) or sleeping sickness, is caused by Trypanosoma brucei gambiense, which is a
chronic form of the disease present in western and central Africa and…
Tsetse Control and the Elimination of Gambian Sleeping Sickness
- MedicinePLoS neglected tropical diseases
- 2016
A crucial finding was that a tiny target consisting of a small square of blue cloth flanked by a similar sized piece of black netting was highly effective and would be about ten times more cost-effective than traps or large targets in control campaigns for the Palpalis (riverine) group tsetse flies responsible for the transmission of the vast majority of HAT.
Human African Trypanosomiasis: Progress and Stagnation.
- Medicine, BiologyInfectious disease clinics of North America
- 2019
References
SHOWING 1-10 OF 188 REFERENCES
Congenital Trypanosomiasis in Child Born in France to African Mother
- MedicineEmerging infectious diseases
- 2016
To the Editor: Sleeping sickness, or human African trypanosomiasis, is a neglected tropical parasitic infection transmitted by the tsetse fly bite. In central and western Africa, trypanosomiasis is…
Is vector control needed to eliminate gambiense human African trypanosomiasis?
- BiologyFront. Cell. Infect. Microbiol.
- 2013
Human African Trypanosomiasis, or sleeping sickness, is a neglected tropical parasitic disease of humans due to trypanosomes transmitted by tsetse flies in sub-Saharan Africa and treatment is still long and difficult to administer despite recent improvements.
Human African trypanosomiasis: a review of non-endemic cases in the past 20 years.
- MedicineInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
- 2011
Chemotherapy of human African trypanosomiasis.
- BiologyCurrent pharmaceutical design
- 2002
Four drugs have been licensed to treat human African trypanosomiasis and two of them, pentamidine and suramin, are used prior to CNS involvement, while melarsoprol is used once parasites are established in the CNS.
Human African Trypanosomiasis in the Democratic Republic of the Congo: A Looming Emergency?
- MedicinePLoS neglected tropical diseases
- 2012
The Democratic Republic of the Congo (DRC) has been forced to gradually scale down active case finding campaigns against human African trypanosomiasis, which is largely funded through bilateral cooperation with Belgium.
Epidemiology of human African trypanosomiasis
- MedicineClinical epidemiology
- 2014
Sustainable elimination of the gambiense HAT, defined as the interruption of the transmission of the disease, was considered as a feasible target for 2030, since rhodesiense H AT is a zoonosis, where the animal reservoir plays a key role, and the interruptionOf the disease’s transmission is not deemed feasible.
Human African trypanosomiasis in non-endemic countries (2000-2010).
- MedicineJournal of travel medicine
- 2012
Centralized distribution of drugs for HAT by WHO enables an HAT surveillance system for non-DECs to be maintained and provides valuable information on disease transmission and complements data collected in DECs.
Control and surveillance of human African trypanosomiasis.
- MedicineWorld Health Organization technical report series
- 2013
Information about new diagnostic approaches, new therapeutic regimens and better understanding of the distribution of the disease with high-quality mapping are provided, forming the basis for an integrated strategy with which it is hoped that elimination of gambiense HAT will be achieved.
Human African Trypanosomiasis Presenting at Least 29 Years after Infection—What Can This Teach Us about the Pathogenesis and Control of This Neglected Tropical Disease?
- MedicinePLoS neglected tropical diseases
- 2014
A unique case of a patient harbouring the parasite for more than three decades before developing stage 2 sleeping sickness is presented.