Human Adipose Tissue-Derived Mesenchymal Stem Cells Target Brain Tumor-Initiating Cells

@inproceedings{Choi2015HumanAT,
  title={Human Adipose Tissue-Derived Mesenchymal Stem Cells Target Brain Tumor-Initiating Cells},
  author={Seung Ah Choi and Ji Yeoun Lee and Sung Eun Kwon and K C Wang and Ji Hoon Phi and Jung Won Choi and Xiong Jie Jin and Ja Yun Lim and Hyunggee Kim and S. -K. Kim and Jeffrey K. Harrison},
  booktitle={PloS one},
  year={2015}
}
In neuro-oncology, the biology of neural stem cells (NSCs) has been pursued in two ways: as tumor-initiating cells (TICs) and as a potential cell-based vehicle for gene therapy. NSCs as well as mesenchymal stem cells (MSCs) have been reported to possess tumor tropism capacities. However, there is little data on the migratory capacity of MSCs toward brain tumor-initiating cells (BTICs). This study focuses on the ability of human adipose tissue derived MSCs (hAT-MSCs) to target BTICs and their… CONTINUE READING
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Human Adipose Tissue-Derived Mesenchymal Stem Cells Target Brain Tumor-Initiating Cells

  • SA Choi, JY Lee, SE Kwon, K-C Wang, JH Phi, JW Choi
  • PLOSONE | DOI:10.1371/journal.pone.0132877 July
  • 2015

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