Human ARHGDIG, a GDP-dissociation inhibitor for Rho proteins: genomic structure, sequence, expression analysis, and mapping to chromosome 16p13.3.

@article{Adra1998HumanAA,
  title={Human ARHGDIG, a GDP-dissociation inhibitor for Rho proteins: genomic structure, sequence, expression analysis, and mapping to chromosome 16p13.3.},
  author={C. Adra and A. Iyengar and F. Syed and I. N. Kanaan and H. Rilo and W. Yu and R. Kheraj and S. R. Lin and T. Horiuchi and S. Khan and S. Weremowicz and B. Lim and C. Morton and D. Higgs},
  journal={Genomics},
  year={1998},
  volume={53 1},
  pages={
          104-9
        }
}
GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activity of GTPases. We recently reported the identification of a new GDI for the Rho-related GTPases named RhoGDIgamma. This gene is now designated ARHGDIG by HUGO. Here, in a detailed analysis of tissue expression of ARHGDIG, we observe high levels in the entire brain, with regional variations. The mRNA is also present at high levels in kidney and pancreas and at moderate levels in spinal cord, stomach, and pituitary… Expand
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