Human β-defensin-2 induction in nasal mucosa after administration of bacterial lysates.


BACKGROUND AND AIMS The airway epithelium produces antimicrobial peptides (AMPs) that prevent colonization of host tissues by a wide range of pathogens. Human β-defensin 2 (hBD-2) is one of the most well-documented AMPs in humans. Several bacterial products can induce production of this peptide. Bacterial immunostimulants containing bacterial lysates have… (More)
DOI: 10.1016/j.arcmed.2011.04.003


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