Human, Pig, and Mouse Interferon-Induced Transmembrane Proteins Partially Restrict Pseudotyped Lentiviral Vectors.

@article{Hornick2016HumanPA,
  title={Human, Pig, and Mouse Interferon-Induced Transmembrane Proteins Partially Restrict Pseudotyped Lentiviral Vectors.},
  author={Andrew L. Hornick and Ni Li and Mayumi Oakland and Paul B. McCray and Patrick L. Sinn},
  journal={Human gene therapy},
  year={2016},
  volume={27 5},
  pages={354-62}
}
Lentiviral vectors are increasingly used in clinical trials to treat genetic diseases. Our research has focused on strategies to improve lentiviral gene transfer efficiency in the airways. Previously we demonstrated that a feline immunodeficiency virus (FIV)-based lentiviral vector pseudotyped with the baculovirus envelope glycoprotein GP64 (GP64-FIV… CONTINUE READING