Huge Fetal Sacrococcygeal Teratoma with a Completely Formed Eye and Intratumoral DNA Ploidy Heterogeneity

@article{Sergi1999HugeFS,
  title={Huge Fetal Sacrococcygeal Teratoma with a Completely Formed Eye and Intratumoral DNA Ploidy Heterogeneity},
  author={Consolato M. Sergi and Volker Ehemann and B. Beedgen and Otwin Linderkamp and Herwart F. Otto},
  journal={Pediatric and Developmental Pathology},
  year={1999},
  volume={2},
  pages={50-57}
}
ABSTRACT Preterm infants and newborns with sacrococcygeal teratomas are at high risk for prenatal and perinatal complications. The prognosis depends on size and histology of the tumor, degree of prematurity, associated malformations, route of delivery, and prompt and complete surgical removal. Virtually any tissue can be present in a sacrococcygeal teratoma, but to date, ocular lens has been documented only as lentinoids (lens-like cells), whereas flow-cytometric data have been variably… Expand
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Comparison of the cytologic and microtopographic characteristics of lentoids that develop in experimental embryo-derived teratomas suggests that the lentoids within the sacrococcygeal teratoma originate by transdifferentiation of cells of the immature neural retina or the pigmented retinal epithelium. Expand
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It is believed that histologic grade and clinical behavior correlate closely in congenital sacrococcygeal teratomas, and a neuroectodermal component is common, and was here proved to have metastasizing capacity. Expand
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