Huge Fetal Sacrococcygeal Teratoma with a Completely Formed Eye and Intratumoral DNA Ploidy Heterogeneity

  title={Huge Fetal Sacrococcygeal Teratoma with a Completely Formed Eye and Intratumoral DNA Ploidy Heterogeneity},
  author={Consolato M. Sergi and Volker Ehemann and Bernhard Beedgen and Otwin Linderkamp and Herwart F. Otto},
  journal={Pediatric and Developmental Pathology},
ABSTRACT Preterm infants and newborns with sacrococcygeal teratomas are at high risk for prenatal and perinatal complications. The prognosis depends on size and histology of the tumor, degree of prematurity, associated malformations, route of delivery, and prompt and complete surgical removal. Virtually any tissue can be present in a sacrococcygeal teratoma, but to date, ocular lens has been documented only as lentinoids (lens-like cells), whereas flow-cytometric data have been variably… 
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A rare presentation of giant cystic retroperitoneal teratoma in adult; A case report.
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Mediastinal teratoma in a neonate with acute respiratory failure
Immediate detection and proper treatment of the large mediastinal teratoma in a neonate was most important to decrease the morbidity and mortality of the infant.


Sacrococcygeal teratomas in infants and children: relationship of histology and prognosis in 40 cases.
It is believed that histologic grade and clinical behavior correlate closely in congenital sacrococcygeal teratomas, and a neuroectodermal component is common, and was here proved to have metastasizing capacity.
Sacrococcygeal teratomas: A review of 68 cases
Immature metanephric tissue in sacrococcygeal teratomas should be interpreted the same way as immature neuroepithelial elements as well as tumors containing malignant elements because of their vastly different prognoses.
Sacrococcygeal teratomas in infants and children.
Benign and malignant sacrococcygeal teratomas
The surgical procedures necessary for the removal of the benign teratomas, the use of combination methods for treatment of the malignant tumors, and the prognosis for cure in both groups of tumors are outlined in this report.
Late occurrence of malignancy following resection of a histologically mature sacrococcygeal teratoma. Report of a case and literature review.
A male patient nearly 40 years old following resection of a histologically mature sacrococcygeal teratoma dies nearly 2 years later with local and regional recurrence of tumor and metastases to lymph nodes, liver, lung, bone, and brain.
Ploidy of primary germ cell tumors of the testis. Pathogenetic and clinical relevance.
The consistent aneuploidy of testicular GCTs of adults might be helpful in the differential diagnosis of primary nongerm cell tumors of the testis, and in differentiating between metastases of testSexual orientation-related tumors and primary extragonadal malignant G CTs.
Neonatal benign sacrococcygeal teratoma may recur in adulthood and give rise to malignancy
A small number of studies have reported recurrence of the tumors beyond childhood, and these are the first studies to report this phenomenon in neonatal SCTs.