Hu-K4 is a ubiquitously expressed type 2 transmembrane protein associated with the endoplasmic reticulum.

@article{Munck2005HuK4IA,
  title={Hu-K4 is a ubiquitously expressed type 2 transmembrane protein associated with the endoplasmic reticulum.},
  author={Antonia Munck and Christopher B{\"o}hm and Nicole Maria Seibel and Zara Hashemol Hosseini and Wolfgang Hampe},
  journal={The FEBS journal},
  year={2005},
  volume={272 7},
  pages={
          1718-26
        }
}
Hu-K4 is a human protein homologous to the K4L protein of vaccinia virus. Due to the presence of two HKD motifs, Hu-K4 was assigned to the family of Phospholipase D proteins although so far no catalytic activity has been shown. The Hu-K4 mRNA is found in many human organs with highest expression levels in the central nervous system. We extended the ORF of Hu-K4 to the 5' direction. As a consequence the protein is 53 amino acids larger than originally predicted, now harbouring a putative… CONTINUE READING
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