Hsp70 duplication in the Drosophila melanogaster species group: how and when did two become five?

@article{Bettencourt2001Hsp70DI,
  title={Hsp70 duplication in the Drosophila melanogaster species group: how and when did two become five?},
  author={Brian R. Bettencourt and Martin E. Feder},
  journal={Molecular biology and evolution},
  year={2001},
  volume={18 7},
  pages={1272-82}
}
To determine how the modern copy number (5) of hsp70 genes in Drosophila melanogaster evolved, we localized the duplication events that created the genes in the phylogeny of the melanogaster group, examined D. melanogaster genomic sequence to investigate the mechanisms of duplication, and analyzed the hsp70 gene sequences of Drosophila orena and Drosophila mauritiana. The initial two-to-four hsp70 duplication occurred 10--15 MYA, according to fixed in situ hybridization to polytene chromosomes… CONTINUE READING