Hsp60 and Hsp10 increase in colon mucosa of Crohn’s disease and ulcerative colitis

@article{Rodolico2010Hsp60AH,
  title={Hsp60 and Hsp10 increase in colon mucosa of Crohn’s disease and ulcerative colitis},
  author={Vito Rodolico and Giovanni Tomasello and Monica Zerilli and Anna Martorana and Alessandro Pitruzzella and Antonella Marino Gammazza and Sabrina David and Giovanni Zummo and Provvidenza Damiani and Salvatore Accomando and Everly Conway de Macario and Alberto J. L. Macario and Francesco Cappello},
  journal={Cell Stress and Chaperones},
  year={2010},
  volume={15},
  pages={877-884}
}
The purpose of this work was to determine in colon mucosa of Crohn’s disease (CD) and ulcerative colitis (UC) in relapse: a) the levels of the chaperonins Hsp60 and Hsp10; b) the quantity of inflammatory cells; and c) if the levels of chaperonins parallel those of inflammation cells. Twenty cases of CD and UC and twenty normal controls (NC) were studied using immunohistochemistry, Western blotting and immunofluorescence. Immunohistochemically, Hsp60 and Hsp10 were increased in both inflammatory… CONTINUE READING
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Heat shock protein-derived T-cell epitopes contribute to autoimmune inflammation in pediatric Crohn’s disease

  • GL Puga Yung, M Fidler, +9 authors S Albani
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  • 2009
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