Hsp and MDR gene upregulation during hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinosis.


e21072 Background: Peritoneal carcinosis (PC) is diagnosed in 10-20% of gastric, colorectal and ovarian cancer. Hyperthermic intraperitoneal chemotherapy (HIPEC) is increasingly integrated into multimodal treatment strategies. We analyzed relevant HSPs that confer resistance to physical stresses (elevated temperatures) as well as profiles of the specific… (More)