Hox is in the hair: a break in colinearity?

  title={Hox is in the hair: a break in colinearity?},
  author={Denis Duboule},
  journal={Genes & development},
  volume={12 1},
During mammalian fetal development, axial structures acquire their specifications through the action of the Hox gene family of transcription factors (for review, see Krumlauf 1994). These are 39 such genes that are responsible for giving spatially restricted cues in a variety of embryonic derivatives, from the neural tube to the intestinal tract. In presomitic mesoderm, for example, level-specific qualitative as well as quantitative differences in HOX protein content will instruct the future… CONTINUE READING


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Hox genes in vertebrate development

P. A. Lawrence

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