Hox in motion: tracking HoxA cluster conformation during differentiation

@inproceedings{Rousseau2014HoxIM,
  title={Hox in motion: tracking HoxA cluster conformation during differentiation},
  author={Mathieu Rousseau and Jennifer Lynn Crutchley and Hisashi Miura and M. Suderman and Mathieu Blanchette and Jos{\'e}e Dostie},
  booktitle={Nucleic acids research},
  year={2014}
}
Three-dimensional genome organization is an important higher order transcription regulation mechanism that can be studied with the chromosome conformation capture techniques. Here, we combined chromatin organization analysis by chromosome conformation capture-carbon copy, computational modeling and epigenomics to achieve the first integrated view, through time, of a connection between chromatin state and its architecture. We used this approach to examine the chromatin dynamics of the HoxA… CONTINUE READING

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