Hox genes in digit development and evolution

@article{Zakany1999HoxGI,
  title={Hox genes in digit development and evolution},
  author={József Zákány and Denis Duboule},
  journal={Cell and Tissue Research},
  year={1999},
  volume={296},
  pages={19-25}
}
Abstract Homeobox genes located in the 5’ part of the HoxA and HoxD complexes are required for proliferation of skeletal progenitor cells of the vertebrate limb. Specific combinations of gene products determine the length of the upper arm (genes belonging to groups 9 and 10), the lower arm (groups 10, 11 and 12) and the digits (groups 11, 12 and 13). In these different domains, individual gene products quantitatively contribute to an overall protein dose, with predominant roles for groups 11… Expand
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