Hox gene cross-regulatory interactions in the embryonic brain of Drosophila

  title={Hox gene cross-regulatory interactions in the embryonic brain of Drosophila},
  author={Simon G Sprecher and Martin Mueller and Lars Kammermeier and David F. Miller and Thomas C Kaufman and Heinrich Reichert and Frank Hirth},
  journal={Mechanisms of Development},
During embryonic development of the Drosophila brain, the Hox gene labial is required for the regionalized specification of the tritocerebral neuromere. In order to gain further insight into the mechanisms of Hox gene action in the CNS, we have studied the molecular and genetic basis of cross-regulatory interactions between labial and other more posterior Hox genes using the GAL4/UAS system for targeted misexpression. Misexpression of posterior Hox genes in the embryonic neuroectoderm results… CONTINUE READING
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of Drosophila

  • F. Hirth, T. Loop, B. Egger, D. F. B. Miller, T. C. Kaufman, H. Reichert
  • 2001
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