Hox cluster organization in the jawless vertebrate Petromyzon marinus.

  title={Hox cluster organization in the jawless vertebrate Petromyzon marinus.},
  author={Allan Force and Angel Amores and John H Postlethwait},
  journal={The Journal of experimental zoology},
  volume={294 1},
Large-scale gene amplifications may have facilitated the evolution of morphological innovations that accompanied the origin of vertebrates. This hypothesis predicts that the genomes of extant jawless fish, scions of deeply branching vertebrate lineages, should bear a record of these events. Previous work suggests that nonvertebrate chordates have a single Hox cluster, but that gnathostome vertebrates have four or more Hox clusters. Did the duplication events that produced multiple vertebrate… CONTINUE READING

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