How yeast can be used as a genetic platform to explore virus-host interactions: from 'omics' to functional studies.

@article{Nagy2014HowYC,
  title={How yeast can be used as a genetic platform to explore virus-host interactions: from 'omics' to functional studies.},
  author={Peter D Nagy and Judit Pogany and Jing-Yi Lin},
  journal={Trends in microbiology},
  year={2014},
  volume={22 6},
  pages={309-16}
}
The yeast Saccharomyces cerevisiae is an advanced model organism that has emerged as an effective host to gain insights into the intricate interactions of viruses with host cells. RNA viruses have limited coding potential and need to coopt numerous host cellular factors to facilitate their replication. To identify the host factors subverted by viruses, high-throughput genomics and global proteomics approaches have been performed with plant viruses such as brome mosaic virus (BMV) and tomato… CONTINUE READING
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