How will bioinformatics influence metabolic engineering?

@article{Edwards1998HowWB,
  title={How will bioinformatics influence metabolic engineering?},
  author={Jeremy S. Edwards and Bernhard O. Palsson},
  journal={Biotechnology and bioengineering},
  year={1998},
  volume={58 2-3},
  pages={
          162-9
        }
}
Ten microbial genomes have been fully sequenced to date, and the sequencing of many more genomes is expected to be completed before the end of the century. The assignment of function to open reading frames (ORFs) is progressing, and for some genomes over 70% of functional assignments have been made. The majority of the assigned ORFs relate to metabolic functions. Thus, the complete genetic and biochemical functions of a number of microbial cells may be soon available. From a metabolic… Expand
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