How well do antidepressants work in older people? A systematic review of Number Needed to Treat.


OBJECTIVES To make direct comparisons between studies of antidepressant treatment of older people using Number Needed to Treat (NNT) analysis. METHODS Medline and Embase Search 1966-1999 and contact with manufacturers of antidepressant drugs asking for any relevant data on file; NNT analyses of outcome in terms of efficacy and adverse effects. RESULTS… (More)


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