How we choose factor VIII to treat hemophilia.

  title={How we choose factor VIII to treat hemophilia.},
  author={P. Mannucci and M. Mancuso and E. Santagostino},
  volume={119 18},
  • P. Mannucci, M. Mancuso, E. Santagostino
  • Published 2012
  • Medicine
  • Blood
  • In high-income countries, the large availability of coagulation factors for replacement therapy of patients with hemophilia A has raised the life expectancy of these lifelong bleeders to that of males from the general population. The practicing clinician is offered a multitude of choices among several commercial brands of factor VIII extracted from human plasma or engineered from mammalian cell cultures by means of recombinant DNA technology. This article has the goal to offer our opinions on… CONTINUE READING
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