How to tell if a new marker improves prediction.


The ability to predict clinical outcomes accurately is critical to the proper management of any human disease. Prostate cancer, with its numerous clinical states, myriad treatment options, and uncertain natural history, has become a popular testing ground for prediction models, and the development of novel prognostic markers continues at a rapid rate… (More)
DOI: 10.1016/j.eururo.2011.04.029


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