How to leverage an endogenous immune defense mechanism: the example of granulocyte colony-stimulating factor.

@article{Hartung2003HowTL,
  title={How to leverage an endogenous immune defense mechanism: the example of granulocyte colony-stimulating factor.},
  author={Thomas Hartung and Sonja von Aulock and Christian M. Schneider and Eugen Faist},
  journal={Critical care medicine},
  year={2003},
  volume={31 1 Suppl},
  pages={S65-75}
}
Our understanding of host defense has exploded during the past two decades. It is temping to take advantage of this knowledge by considering the modulation and control of these mechanisms as therapeutic options. In intensive care medicine, the aim is usually to block an overwhelming inflammatory response, which represents the "bad" side of the double-edged sword of host defense. The obvious danger of such treatment strategies is that impairing the inflammatory reaction means impairing host… CONTINUE READING
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