How to improve the clinical diagnosis of Creutzfeldt-Jakob disease.

  title={How to improve the clinical diagnosis of Creutzfeldt-Jakob disease.},
  author={Sigrid Poser and Brit Mollenhauer and A Kraubeta and Inga Zerr and B J Steinhoff and Andreas Schr{\"o}ter and Michael Finkenstaedt and Walter J. Schulz-Schaeffer and Hans A. Kretzschmar and Klaus Felgenhauer},
  journal={Brain : a journal of neurology},
  volume={122 ( Pt 12)},
This paper describes a prospective follow-up of 364 patients initially notified as suspected Creutzfeldt-Jakob disease to a Surveillance Unit in Göttingen, Germany. Six patients were diagnosed as having genetic prion disease by blood analysis and were excluded from the study. After examination and review of the remaining 358, 193 were classified as probable Creutzfeldt-Jakob disease. However, autopsy revealed that five of the 193 did not have Creutzfeldt-Jakob disease (four cases, Alzheimer's… CONTINUE READING
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