How to hide zinc in a small protein.


Small cysteine-rich proteins (metallothioneins) and related domains of some large proteins (e.g., lysine methyltransferases) bind tri- and tetranuclear zinc clusters with topologies resembling fragments of Zn(II) sulfide minerals. These clusters are ubiquitous in animals, plants, and bacteria. Bacterial metallothioneins can also contain histidines as… (More)


Cite this paper

@article{Blindauer2005HowTH, title={How to hide zinc in a small protein.}, author={Claudia Andrea Blindauer and Peter J Sadler}, journal={Accounts of chemical research}, year={2005}, volume={38 1}, pages={62-9} }