• Corpus ID: 39500835

How to convert from traditional cyclosporine to the microemulsion formulation in stable renal transplant patients?

@article{Gaspari1998HowTC,
  title={How to convert from traditional cyclosporine to the microemulsion formulation in stable renal transplant patients?},
  author={Flavio Gaspari and Norberto Perico and Roberto Pisoni and M F Anedda and O Signorini and Raffaele Caruso and Eliana Gotti and Giuseppe Remuzzi},
  journal={Clinical transplantation},
  year={1998},
  volume={12 5},
  pages={
          379-90
        }
}
How to convert from traditional cyclosporine (CsA) to the microemulsion formulation in stable renal transplant patients is still a matter of debate. The present study was designed to evaluate the effects of changeover from traditional Sandimmune to Neoral formulation at two dose-ratio conversions on CsA pharmacokinetics, safety and tolerability particularly in terms of renal function. Thirty outpatients regularly followed at our Clinical Research Center were randomized to 1:1 or 1:0.75 dose… 
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