How to be rational about empirical success in ongoing science: The case of the quantum nose and its critics.

  title={How to be rational about empirical success in ongoing science: The case of the quantum nose and its critics.},
  author={Ann-Sophie Barwich},
  journal={Studies in history and philosophy of science},
  • A. Barwich
  • Published 1 June 2018
  • Philosophy
  • Studies in history and philosophy of science
The Value of Failure in Science: The Story of Grandmother Cells in Neuroscience
This article advances the heuristics of failure analysis, meaning the explicit treatment of certain ideas or models as failures, and is illustrated with the contested idea of a hypothetical neuron that encodes a highly specific but complex stimulus, such as the image of one’s grandmother.
Monist and Pluralist Approaches on Underdetermination: A Case Study in Evolutionary Microbiology
Philosophers have usually highlighted how the weakness and paucity of historical evidence underdetermine the choice between rival historical explanations. Focusing underdetermination on the link
Fishing for Genes: How the Largest Gene Family in the Mammalian Genome was Found (and Why Idiosyncrasy in Exploration Matters)
It is argued that the individual researcher is not a replaceable epistemic element in discovery analysis, including interviews with Buck and other actors key to developments in late 1980s olfaction.
Sensory Perception of Non‐Deuterated and Deuterated Organic Compounds
Quantum chemical calculations give evidence that deuterated octanoic acid binds more strongly to a model receptor than non‐deuterated, and the binding of the non‐Deuterated molecule is stronger with acetone, which indicates that the isotope effect is very molecule‐specific.
Molecular Basis of Mammalian Odor Discrimination: A Status Report.
  • E. Block
  • Biology
    Journal of agricultural and food chemistry
  • 2018
Based on cumulative evidence from OR deorphaning and olfactory receptor neuron activation studies, a receptor-ligand docking model rather than an alternative bond vibration model is suggested to best explain the molecular basis of the exquisitely sensitive odor discrimination in mammals.


Explication Work for Science and Philosophy
  • J. Schickore
  • Philosophy
    Journal of the Philosophy of History
  • 2018
This article disentangles the various assumptions and expectations tied to case studies, to testing philosophy through cases, and to historical adequacy. Several notions of historical adequacy are
Life at the Frontier: The Relevance of Heuristic Appraisal to Policy
Attention is called on to the importance of heuristic appraisal for “frontier epistemology” and to policy formation in the study of weak modes of reasoning and evaluation, especially relevant to socio-economic policy.
A novel defense of scientific realism
Vigorous and controversial, this book develops a sustained argument for a realist interpretation of science, based on a new analysis of the concept of predictive novelty. Identifying a form of
Exceeding Our Grasp: Science, History, and the Problem of Unconceived Alternatives
The incredible achievements of modern scientific theories lead most of us to embrace scientific realism: the view that our best theories offer us at least roughly accurate descriptions of otherwise
Empirical Success or Explanatory Success: What Does Current Scientific Realism Need to Explain?
Against the well‐known objection that in the history of science there are many theories that are successful but false, Psillos offers a three‐pronged defense of scientific realism as the best
Doing Science, Writing Science*
This article identifies a fundamental distinction in scientific practice: the mismatch between what scientists do and what they state they did when they communicate their findings in their
More Thoughts on HPS: Another 20 Years Later
  • J. Schickore
  • Philosophy, Education
    Perspectives on Science
  • 2011
This essay deals with the recent history of the disputes about the relation between history and philosophy of science and the merits and prospects of HPS as an intellectual endeavor. I begin with a
The Hidden History of Phlogiston How Philosophical Failure Can Generate Historiographical Refinement
Historians often feel that standard philosophical doctrines about the nature and development of science are not adequate for representing the real history of science. However, when philosophers of
A Philosopher’s Guide to Empirical Success
The simple question, what is empirical success? turns out to have a surprisingly complicated answer. We need to distinguish between meritorious fit and ‘fudged fit’, which is akin to the distinction
Narrative and evidence. How can case studies from the history of science support claims in the philosophy of science?