How the study of Helicobacter infection can contribute to the understanding of carcinoma development.

@article{Stoicov2009HowTS,
  title={How the study of Helicobacter infection can contribute to the understanding of carcinoma development.},
  author={C. Stoicov and H. Li and J. Cerny and J. Houghton},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2009},
  volume={15 9},
  pages={
          813-22
        }
}
  • C. Stoicov, H. Li, +1 author J. Houghton
  • Published 2009
  • Biology, Medicine
  • Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
The inflammatory environment dramatically impacts the formation of cancer at many levels, acting on the stem cell to foster the initiation of cancer all the way through its contribution to metastatic disease. Using Helicobacter-induced gastric cancer as an example, it can be seen that, early on, chronic inflammation exhausts tissue stem cells, forcing the remaining stem cells to work overtime and calling in replacement cells from marrow sources. Marrow-derived stromal cells orchestrate growth… Expand
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