How the mother can help: studying maternal Wnt signaling by anti-sense-mediated depletion of maternal mRNAs and the host transfer technique.


Early development in Xenopus laevis is controlled by maternal gene products synthesized during oogenesis. The dorsal/ventral and anterior/posterior axes are established as a result of canonical Wnt signaling activity. The functions of maternal genes in embryonic development are most effectively studied by introducing anti-sense, oligos complementary to… (More)
DOI: 10.1007/978-1-60327-469-2_26


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