How the excluded volume architecture influences ion-mediated forces between proteins.

@article{Dahirel2007HowTE,
  title={How the excluded volume architecture influences ion-mediated forces between proteins.},
  author={Vincent Dahirel and Marie Jardat and J F Dufr{\^e}che and Pierre Turq},
  journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
  year={2007},
  volume={76 4 Pt 1},
  pages={040902}
}
The effective interactions between model proteins of various shapes are computed by means of Monte Carlo simulations. In particular, we determine how the modification of the excluded volume architecture influences both entropic and purely electrostatic ion-mediated forces between proteins. We find that interprotein interactions are strongly affected by protein shape, which results in a high decrease of electrostatic screening for typical active site geometries. Effective interactions are then… CONTINUE READING