How the evolution of multicellularity set the stage for cancer

@inproceedings{Trigos2018HowTE,
  title={How the evolution of multicellularity set the stage for cancer},
  author={Anna Sof{\'i}a Trigos and Richard B Pearson and Anthony T. Papenfuss and David L. Goode},
  booktitle={British Journal of Cancer},
  year={2018}
}
Neoplastic growth and many of the hallmark properties of cancer are driven by the disruption of molecular networks established during the emergence of multicellularity. Regulatory pathways and molecules that evolved to impose regulatory constraints upon networks established in earlier unicellular organisms enabled greater communication and coordination between the diverse cell types required for multicellularity, but also created liabilities in the form of points of vulnerability in the network… CONTINUE READING