How stress influences the immune response.

@article{Padgett2003HowSI,
  title={How stress influences the immune response.},
  author={D. Padgett and R. Glaser},
  journal={Trends in immunology},
  year={2003},
  volume={24 8},
  pages={
          444-8
        }
}
Abstract In response to a stressor, physiological changes are set into motion to help an individual cope with the stressor. However, chronic activation of these stress responses, which include the hypothalamic–pituitary–adrenal axis and the sympathetic–adrenal–medullary axis, results in chronic production of glucocorticoid hormones and catecholamines. Glucocorticoid receptors expressed on a variety of immune cells bind cortisol and interfere with the function of NF-κB, which regulates the… Expand
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