How stable is the hepatitis C virus (HCV)? Environmental stability of HCV and its susceptibility to chemical biocides.

@article{Ciesek2010HowSI,
  title={How stable is the hepatitis C virus (HCV)? Environmental stability of HCV and its susceptibility to chemical biocides.},
  author={Sandra Ciesek and Martina Friederike Friesland and Joerg Steinmann and Britta Becker and Heiner Wedemeyer and Michael P. Manns and Jochen Steinmann and Thomas Pietschmann and Eike Steinmann},
  journal={The Journal of infectious diseases},
  year={2010},
  volume={201 12},
  pages={
          1859-66
        }
}
BACKGROUND In the absence of a cell culture system for propagation of the hepatitis C virus (HCV), the antiviral activity of disinfectants against HCV was extrapolated from studies with the bovine viral diarrhea virus. The recent development of an HCV infection system allowed the direct assessment of environmental stability and susceptibility to chemical disinfectants. METHODS Studies were performed using cell-culture grown HCV. Infectivity was determined by limiting dilutions. HCV RNA levels… CONTINUE READING

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