[How safe is the recombinant human growth hormone?]


In this paper, several aspects related to the safety of the use of biosynthetic human growth hormone are reviewed. For example, its classification as a biosynthetic drug, the phases that need to be performed in Mexico to verify its safety (obtaining, purification, preclinical studies, clinical trials, and finally observational clinical studies), as well as the evidence that exists in relation to the association of intracranial hypertension, muscular events, scoliosis, slipped capital femoral epiphysis, obstructive sleep apnea, pancreatitis, alterations in cortisol, thyroid hormones alterations, cardiovascular disease, metabolic risk, mortality and cancer, adverse events not related to its use, and finally dosing and safety.

Cite this paper

@article{CalzadaLen2017HowSI, title={[How safe is the recombinant human growth hormone?]}, author={Ra{\'u}l Calzada-Le{\'o}n}, journal={Revista medica del Instituto Mexicano del Seguro Social}, year={2017}, volume={55 3}, pages={341-352} }