How reliable is the clinical exam in detecting ocular chlamydial infection?

@article{Miller2004HowRI,
  title={How reliable is the clinical exam in detecting ocular chlamydial infection?},
  author={Kevin C. Miller and Greg F. Schmidt and Muluken Melese and Wondu Alemayehu and Elizabeth Yi and Vicky Cevallos and Cathy Donnellan and Lynn Olinger and Demeke Fantaye and Bruce D. Gaynor and John P. Whitcher and Thomas M. Lietman},
  journal={Ophthalmic epidemiology},
  year={2004},
  volume={11 3},
  pages={
          255-62
        }
}
PURPOSE To describe the relationship between the clinical exam for trachoma and the polymerase chain reaction (PCR) for ocular chlamydia. METHODS One hundred children in a trachoma-endemic area of Ethiopia were examined three times and swabbed twice for PCR analysis. The assays were compared, and an analysis of the variance between exam and PCR was performed. RESULTS Inter-examiner agreement was 0.57 (Cohen's kappa), inter-PCR agreement 0.98, and agreement between examiner and PCR, 0.26-0… CONTINUE READING

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