How oxygen attacks [FeFe] hydrogenases from photosynthetic organisms.

@article{Stripp2009HowOA,
  title={How oxygen attacks [FeFe] hydrogenases from photosynthetic organisms.},
  author={Sven Timo Stripp and Gabrielle Goldet and Caterina Brandmayr and Oliver Sanganas and Kylie A Vincent and Michael Haumann and Fraser A Armstrong and Thomas Happe},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2009},
  volume={106 41},
  pages={17331-6}
}
Green algae such as Chlamydomonas reinhardtii synthesize an [FeFe] hydrogenase that is highly active in hydrogen evolution. However, the extreme sensitivity of [FeFe] hydrogenases to oxygen presents a major challenge for exploiting these organisms to achieve sustainable photosynthetic hydrogen production. In this study, the mechanism of oxygen inactivation of the [FeFe] hydrogenase CrHydA1 from C. reinhardtii has been investigated. X-ray absorption spectroscopy shows that reaction with oxygen… CONTINUE READING