How much residual plasma may cause TRALI?

  title={How much residual plasma may cause TRALI?},
  author={Nay Win and Catherine Eluned Chapman and Kristian M Bowles and Ann G. Green and Suzanne Bradley and Drew Edmondson and Jonathan P. Wallis},
  journal={Transfusion medicine},
  volume={18 5},
Although passive infusion of plasma-rich components containing white blood cell (WBC) antibodies are responsible for majority of the reported transfusion-related acute lung injury (TRALI) cases, the minimum volume of residual plasma, which might trigger TRALI, is not known. We report three cases of TRALI where the implicated donor component contained between 10 and 20 mL of residual plasma. Two cases were related to transfusion of red blood cells prepared in optimal additive solution, and the… CONTINUE READING
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