How much non-coding DNA do eukaryotes require?

@article{Ahnert2008HowMN,
  title={How much non-coding DNA do eukaryotes require?},
  author={S. Ahnert and T. Fink and A. Zinovyev},
  journal={Journal of theoretical biology},
  year={2008},
  volume={252 4},
  pages={
          587-92
        }
}
Despite tremendous advances in the field of genomics, the amount and function of the large non-coding part of the genome in higher organisms remains poorly understood. Here we report an observation, made for 37 fully sequenced eukaryotic genomes, which indicates that eukaryotes require a certain minimum amount of non-coding DNA (ncDNA). This minimum increases quadratically with the amount of DNA located in exons. Based on a simple model of the growth of regulatory networks, we derive a… Expand
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