How much insulin-like growth factor I (IGF-I) circulates? Impact of standardization on IGF-I assay accuracy.


There is a significant systematic difference between the normal range obtained from ethylenediamine tetraacetate plasma samples using the Genentech total insulin-like growth factor I (IGF-I) RIA and normal ranges for other total IGF-I RIAs. To determine whether the quality of the assay standard was the cause of this systematic difference, we analyzed… (More)


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