How much heparin do we really need to go on pump? A rethink of current practices.

@article{Shuhaibar2004HowMH,
  title={How much heparin do we really need to go on pump? A rethink of current practices.},
  author={Maher Nicolas Shuhaibar and Martin Hargrove and M H Millat and Aonghus P O'Donnell and Thomas M Aherne},
  journal={European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery},
  year={2004},
  volume={26 5},
  pages={947-50}
}
OBJECTIVES Patients undergoing myocardial revascularisation using extracorporeal circulation require heparin anticoagulation. We aimed to evaluate the effect of reducing heparin dosage on target activated clotting time (ACT) and postoperative blood loss. METHODS In a prospective randomised trial, 195 patients undergoing isolated primary CABG were randomised into four groups A, B, C, and D receiving an initial heparin dosage of 100, 200, 250 and 300 iu/kg, respectively. Extra incremental… CONTINUE READING