How microRNAs facilitate reprogramming to pluripotency.

  title={How microRNAs facilitate reprogramming to pluripotency.},
  author={Frederick Anokye-Danso and Melinda Snitow and Edward E Morrisey},
  journal={Journal of cell science},
  volume={125 Pt 18},
The ability to generate pluripotent stem cells from a variety of cell and tissue sources through the ectopic expression of a specific set of transcription factors has revolutionized regenerative biology. The development of this reprogramming technology not only makes it possible to perform basic research on human stem cells that do not have to be derived from embryos, but also allows patient-specific cells and tissues to be generated for therapeutic use. Optimizing this process will probably… CONTINUE READING
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