How many patients? How many limbs? Analysis of patients or limbs in the orthopaedic literature: a systematic review.

Abstract

BACKGROUND Clinical studies assessing orthopaedic interventions often include data from two limbs or multiple joints within single individuals. Without appropriate design or statistical approaches to address within-individual correlations, this practice may contribute to false precision and possible bias in estimates of treatment effect. We conducted a… (More)

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Cite this paper

@article{Bryant2006HowMP, title={How many patients? How many limbs? Analysis of patients or limbs in the orthopaedic literature: a systematic review.}, author={Dianne M. Bryant and Thomas C Havey and Robin Roberts and Gordon H. Guyatt}, journal={The Journal of bone and joint surgery. American volume}, year={2006}, volume={88 1}, pages={41-5} }