How low is the alpha/beta ratio for prostate cancer?

  title={How low is the alpha/beta ratio for prostate cancer?},
  author={Jian Wang and Mariana Guerrero and X. Allen Li},
  journal={International journal of radiation oncology, biology, physics},
  volume={55 1},
PURPOSE It has been suggested recently that the alpha/beta ratio for human prostate cancer is low (around 1.5 Gy), and much debate on the evidence for such a low value is ongoing. Analyses reported so far ignored the contribution of tumor repopulation. Extremely low alpha values and unrealistic cell numbers of tumor clonogens are found in these studies. In this paper, we present a comprehensive analysis of the updated clinical data to derive a self-consistent set of parameters for the linear… CONTINUE READING

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