How is the indentation modulus of bone tissue related to its macroscopic elastic response? A validation study.

@article{Hengsberger2003HowIT,
  title={How is the indentation modulus of bone tissue related to its macroscopic elastic response? A validation study.},
  author={Stefan Hengsberger and Johanna Enstr{\"o}m and Françoise Peyrin and Ph Zysset},
  journal={Journal of biomechanics},
  year={2003},
  volume={36 10},
  pages={1503-9}
}
This work consists of the validation of a novel approach to estimate the local anisotropic elastic constants of the bone extracellular matrix using nanoindentation. For this purpose, nanoindentation on two planes of material symmetry were analyzed and the resulting longitudinal elastic moduli compared to the moduli measured with a macroscopic tensile test. A combined lathe and tensile system was designed that allows machining and testing of cylindrical microspecimens of approximately 4mm in… CONTINUE READING