How is the effectiveness of immune surveillance impacted by the spatial distribution of spreading infections?

@inproceedings{Kadolsky2015HowIT,
  title={How is the effectiveness of immune surveillance impacted by the spatial distribution of spreading infections?},
  author={Ulrich D. Kadolsky and Andrew J. Yates},
  booktitle={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  year={2015}
}
What effect does the spatial distribution of infected cells have on the efficiency of their removal by immune cells, such as cytotoxic T lymphocytes (CTL)? If infected cells spread in clusters, CTL may initially be slow to locate them but subsequently kill more rapidly than in diffuse infections. We address this question using stochastic, spatially explicit… CONTINUE READING

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