How golden is silence? Teaching undergraduates the power and limits of RNA interference.

@article{Kuldell2006HowGI,
  title={How golden is silence? Teaching undergraduates the power and limits of RNA interference.},
  author={Natalie H Kuldell},
  journal={CBE life sciences education},
  year={2006},
  volume={5 3},
  pages={247-54}
}
It is hard and getting harder to strike a satisfying balance in teaching. Time dedicated to student-generated models or ideas is often sacrificed in an effort to "get through the syllabus." I describe a series of RNA interference (RNAi) experiments for undergraduate students that simultaneously explores fundamental concepts in gene regulation, develops cutting-edge laboratory skills, and embraces student-directed learning. Students design a small interfering RNA (siRNA) against luciferase, add… CONTINUE READING

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RNAi: A Guide to Gene Silencing, Cold Spring Harbor, NY: Cold Spring Harbor

  • G. J. Hannon
  • 2003
Highly Influential
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