How fibroblast growth factor 23 works.

@article{Liu2007HowFG,
  title={How fibroblast growth factor 23 works.},
  author={Shiguang Liu and Leigh Quarles},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2007},
  volume={18 6},
  pages={1637-47}
}
There is a discontinuum of hereditary and acquired disorders of phosphate homeostasis that are caused by either high or low circulating levels of the novel phosphaturic hormone fibroblastic growth factor 23 (FGF23). Disorders that are caused by high circulating levels of FGF23 are characterized by hypophosphatemia, decreased production of 1,25-dihydroxyvitamin D, and rickets/osteomalacia. On the other end of the spectrum are disorders that are caused by low circulating levels of FGF23, which… CONTINUE READING

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